Proton Pump Inhibitors Cause Dementia

According to the FDA: Proton Pump Inhibitors that are found in Antacid medicine can now be linked to Dementia

WHAT ARE PPI’s?

A new study has been conducted that is able to link proton pump inhibitors (PPI’s). PPI’s are commonly found in drugs that treat heartburn, peptic ulcers, and other acid-related disorders of the upper gastrointestinal tract areas of the body. The PPI’s that are found in these medicines are now believed to cause Dementia among older patients past their 70’s after extended use.

HOW DO PPI’s CAUSE DEMENTIA?

According to research findings, there is strong evidence supporting the fact that PPI’s can cause serious vitamin B12 deficiency. Other Studies have proven that vitamin B12 deficiency is directly linked with cognitive decline, and can also be linked with various other disorders such as:

• paranoia or hallucinations
• yellow jaundiced skin
• inflamed or swollen tongue
• anemia
• and a list of other symptoms as well

According to The European Archives of Psychiatry and Clinical Neuroscience:

“Data were derived from a longitudinal, multicenter cohort study in elderly primary care patients, the German Study on Aging, Cognition and Dementia in Primary Care Patients (AgeCoDe), including 3,327 community-dwelling persons aged ≥75 years. From follow-up 1 to follow-up 4 (follow-up interval 18 months), we identified a total of 431 patients with incident any dementia, including 260 patients with Alzheimer’s disease. We used time-dependent Cox regression to estimate hazard ratios of incident any dementia and Alzheimer’s disease. Potential confounders included in the analysis comprised age, sex, education, the Apolipoprotein E4 (ApoE4) allele status, polypharmacy, and the comorbidities depression, diabetes, ischemic heart disease, and stroke. Patients receiving PPI medication had a significantly increased risk of any dementia [Hazard ratio (HR) 1.38, 95 % confidence interval (CI) 1.04–1.83] and Alzheimer’s disease (HR 1.44, 95 % CI 1.01–2.06) compared with nonusers. Due to the major burden of dementia on public health and the lack of curative medication, this finding is of high interest to research on dementia and provides indication for dementia prevention.”

Cases Including Proton Pump Inhibitors:

Lawsuits including Proton Pump Inhibitors can be linked to hip fractures, spinal fractures, wrist fractures. It’s estimated that 113.4 million prescriptions are written for PPI’s that are used to treat various conditions such as:

• Gastroesophageal Reflux Disease (Gerd)
• Stomach Ulcers
• Heart Burn
• Other Stomach Issues

In March of 2011 the FDA mandated that the makers of these PPI’s include information about the potential risk of low magnesium in the WARNINGS sections of the prescription PPI’s. Drugs such as: Nexium, Dexilant, Prilosec, Zegerid, Prevacid, Protonix, AcipHex, and Vimovo. Because low magnesium levels can cause severe side effects such as broken bones. Some patients suffer from these side effects and don’t even know the cause.

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