Zelnorm Ischemic Colitis
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Zelnorm Ischemic Colitis
The drug Zelnorm was approved by the FDA in 2002 for use in treating irritable bowel syndrome (IBS) in female patients. Specifically, it was targeted at symptoms of constipation and bloating. At that time, the FDA required a warning of diarrhea as a potential Zelnorm side effect. In 2004, the FDA demanded a new warning regarding Zelnorm’s side effects: the potential of an occurrence of ischemic colitis while using the drug.
In general, ischemic conditions are physical restriction of blood flow to a particular area of the body. Zelnorm ischemic colitis refers to restricted blood flow to the intestines. The colitis is a flare-up of IBS; the observed symptoms with Zelnorm ischemic colitis included severe diarrhea; bloody diarrhea and/or worsening abdominal pain. The FDA was sufficiently concerned that they insisted on an additional label warning for Zelnorm and ischemic colitis.
Zelnorm was taken off the market in March of 2007 because the FDA saw a correlation of cardiovascular incidents and the use of the drug. Those cardiovascular problems – such as angina and strokes – involved the restriction of blood flow to the heart. First Zelnorm ischemic colitis showed a tendency of the drug to restrict blood flow; ultimately its possible effect on blood flow to the heart resulted in Zelnorm being pulled from the shelves.
The list of side effects from the drug is extensive; Zelnorm ischemic colitis is but one of them. If you or a family member suffered colitis attacks or a surge in intestinal difficulties while using Zelnorm, you might consider discussing your experience with one of our medical/legal experts. There are a number of product liability suits pending on Zelnorm and your case might be a viable addition.
